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Anouz, Reema (Biomedical Materials Department, Martin Luther University Halle-Wittenberg)poster
“ActiveLayers” is a platform technology for building medical multilayer films based on layer-by-layer technology. It is characterized by its biocompatibility, environmental friendliness, modularity and multi-functionality where it can be optimized and adjusted to treat several medical problems such as; chronic wounds, non-healing bone fractures, periodontal regeneration and postoperative...
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Sierra Sánchez, Álvaro (Cell Production and Tissue Engineering Unit, Virgen de las Nieves University Hospital, 18014, Granada, Spain)poster
"Introduction: In recent years new therapies, such as skin cell lines injection and bioengineered autologous skin substitutes (BASS) technology, have emerged to promote re-epithelialization of damaged areas such as cutaneous wounds and ulcers or to treat patients with severe burns. Antiseptics are commonly used during wound healing to avoid serious infections, but some of them could have the...
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Badali, Elham (Iran University of Medical Sciences )poster
Electrospun fiber comprising bioactive substrates has potential to implant into the wound site as a reliable therapeutic approach in tissue regeneration. Here, electrospun polyvinyl alcohol conjugated tyramine (PVA-Tyr) and collagen (Col) fibrous mat containing chitosan nanoparticle loaded with epigallocatechin 3-gallate (NCs-EGCG) developed and the composite was applied to evaluate in vivo...
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Hautmann, Adrian (MLU Halle-Wittenberg)poster
"Introduction
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Chronic skin wounds place a high burden on patients and health systems. In this study, we developed a composite of an electrospun fleece and a freestanding multilayer film, to combine their respective advantages.
Methodology
A gelatin solution was electrospun and the resulting fleece partially crosslinked in formaldehyde vapor. Spray coating was employed to build up a... -
Slowik, Klaudia (The School of Clinical Dentistry, The University of Sheffield)poster
"Introduction
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Wisdom tooth extraction is one of the most common surgeries carried out in the UK, and is notorious for causing post-operative complications. 1 in 6 patients experience a condition called alveolar osteitis “dry-socket” after wisdom tooth removal; a condition where the blood clot is lost and the extraction socket becomes painful. The condition is a serious problem and causes a... -
Chato-Astrain, Jesús (Department of Histology (Tissue Engineering Group), University of Granada, Spain. Instituto de investigación Biosanitaria ibs. GRANADA, Spain)poster
"Introduction: Severe skin lesions can be life-threatening conditions, especially in burnt patients. We recently described the UGRSKIN model of bioartificial human skin generated by tissue engineering as an ATMP1. Although preliminary clinical results are promising, the biofabrication procedure requires long periods of time due to the need of obtaining abundant keratinocyte cell populations...
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Lackington, William Arthur (Empa)poster
Titanium-based dental implants have been highly optimized to enhance osseointegration, but little attention has been given to the soft tissue-implant interface, despite being a major contributor to long term implant stability. This is strongly linked to a lack of model systems that enable the reliable evaluation of soft tissue-implant interactions. Current in vitro platforms to assess these...
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Wiśniewska, Joanna (Department of Biological Function of Food, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences in Olsztyn, 10-748)poster
"Introduction
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Adipose-derived stem cell (ASC) are increasingly recognized as a vital tool for cell-based therapy. Hypoxic pre-conditioning of ASCs provides thier functional enhancement and makes the cells more attractive for translational science. Recently, ASCs from livestock animals have gained increased attention due to their promising role in developing regenerative medicine protocols... -
Ximenes-Carballo, Celia (Institute for Bioengineering of Catalonia (IBEC))poster
"Introduction: Chronic wounds represent a major burden in human society, and their prevalence is expected to increase due to the upward trend of an aging population, incidence of diabetes, and obesity. In Europe, one out of five hospitalized patients suffers from a pressure ulcer. Moreover, the costs associated with its extensive care treatments are high; about 25 billion dollars are spent...
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Gibot, Laure (Laboratoire des IMRCP, Université de Toulouse, CNRS UMR 5623, Université Toulouse III - Paul Sabatier)poster
"Introduction. Impairment of extracellular matrix (ECM) remodeling is observed in tumour microenvironment or fibrosis and results in excessive collagen production and/or its decreased degradation by metalloproteinases (MMPs). Due to its pivotal role in tissue architectures and functions, ECM components and the proteins that regulate ECM remodeling are thus promising therapeutic targets for...
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Pavlík, Vojtěch (Contipro, a.s.)poster
"Introduction: Many refractory chronic wounds are infected. Hyaluronan chloramide (HA-Cl) is a novel derivative that combines pro-regenerative hyaluronan and antimicrobial chlorine. While the synthesis and stability of HA-Cl were described recently1, its oxidative activity, efficacy against bacteria, and safety in wounds remain to be evaluated.
Methodology: The rate of substrate oxidation...
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Chang, Shwu-jen (Department of Biomedical Engineering, I-Shou University)poster
Keloids are abnormal scar tissue characterized by excessive proliferation of fibroblast and overabundance of collagen. The keloids often occur on earlobes, shoulders, back of the neck and the chest. To date, the therapeutic treatment of hypertrophic scar includes corticosteroid injection, laser therapy, cryotherapy, radiotherapy, and surgical scar revision. However, none of the above methods...
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Verdolino, Davide (University of Manchester)poster
"Introduction
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Wound healing is a complex process that involves numerous cell types, cytokines, chemokines, growth factors and extracellular matrix (ECM) components, which work synergistically to achieve healing1,2. When the healing process fails to proceed through the four physiological phases, the wound is referred to as a chronic wound1,2,4,5. Chronic wounds are a significant global... -
Vondrovic, Štěpán (Contipro a.s.)poster
"Introduction
Using nanofibrous materials for wound healing is very promising yet still challenging. The dressing is usually a composite made of several layers, with a specific role to ensure proper moisture of the wound, breathability, low adhesiveness to the wound and prevention of the infection. One of the benefits that nanofibers have is the ability to easily incorporate antimicrobial...
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Godoi, Manuella (Federal University of Santa Catarina- UFSC/ Biocelltis)poster
"Burned skin wound treatment is one of the most expensive burdens on healthcare systems worldwide. The severity and extension of burn trauma could elevate the rate of hospitalization, and patients with burn wounds are especially vulnerable to infections. Burn injuries are very challenging to manage since it causes loss of the integrity of large portions of the skin, leading to major disability...
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